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mouse monoclonal anti β ngf 768 human antibody  (R&D Systems)


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    R&D Systems mouse monoclonal anti β ngf 768 human antibody
    Mouse Monoclonal Anti β Ngf 768 Human Antibody, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 6 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mouse monoclonal anti β ngf 768 human antibody/product/R&D Systems
    Average 90 stars, based on 6 article reviews
    mouse monoclonal anti β ngf 768 human antibody - by Bioz Stars, 2026-02
    90/100 stars

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    MSCs induce <t>NGF</t> demethylation to regulate the expression of KRT17 and FOXJ1. A MSCs reverse the methylation of transcription factors and the regulatory network of target genes during TEC aging (orange triangles represent transcription factors, and blue circles represent target genes). B The transcription factor NGF was associated with the RNA-seq expression of the target genes KRT17 and FOXJ1 during the reversal of TEC senescence by MSCs. The horizontal coordinate represents the expression of the transcription factor NGF, and the ordinate represents the expression of the target gene. C The mRNA expression levels of demethylated NGF, KRT17 and FOXJ1 were analyzed via qPCR. D The expression of NGF was detected by immunofluorescence (400×). E The expression of the TEC proliferation <t>marker</t> <t>Ki67</t> was detected by immunofluorescence (400×). F Regulatory role of decreased methylation of the NGF/KRT17/FOXJ1 axis in the MSC-mediated reversal of TEC senescence. The measured values represent the mean ± standard deviation (`X ± s) of three replicate experiments. ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001).
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    Image Search Results


    MSCs induce NGF demethylation to regulate the expression of KRT17 and FOXJ1. A MSCs reverse the methylation of transcription factors and the regulatory network of target genes during TEC aging (orange triangles represent transcription factors, and blue circles represent target genes). B The transcription factor NGF was associated with the RNA-seq expression of the target genes KRT17 and FOXJ1 during the reversal of TEC senescence by MSCs. The horizontal coordinate represents the expression of the transcription factor NGF, and the ordinate represents the expression of the target gene. C The mRNA expression levels of demethylated NGF, KRT17 and FOXJ1 were analyzed via qPCR. D The expression of NGF was detected by immunofluorescence (400×). E The expression of the TEC proliferation marker Ki67 was detected by immunofluorescence (400×). F Regulatory role of decreased methylation of the NGF/KRT17/FOXJ1 axis in the MSC-mediated reversal of TEC senescence. The measured values represent the mean ± standard deviation (`X ± s) of three replicate experiments. ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001).

    Journal: Regenerative Therapy

    Article Title: Mesenchymal stem cells reverse thymus aging by reprogramming the DNA methylation of thymic epithelial cells

    doi: 10.1016/j.reth.2024.03.008

    Figure Lengend Snippet: MSCs induce NGF demethylation to regulate the expression of KRT17 and FOXJ1. A MSCs reverse the methylation of transcription factors and the regulatory network of target genes during TEC aging (orange triangles represent transcription factors, and blue circles represent target genes). B The transcription factor NGF was associated with the RNA-seq expression of the target genes KRT17 and FOXJ1 during the reversal of TEC senescence by MSCs. The horizontal coordinate represents the expression of the transcription factor NGF, and the ordinate represents the expression of the target gene. C The mRNA expression levels of demethylated NGF, KRT17 and FOXJ1 were analyzed via qPCR. D The expression of NGF was detected by immunofluorescence (400×). E The expression of the TEC proliferation marker Ki67 was detected by immunofluorescence (400×). F Regulatory role of decreased methylation of the NGF/KRT17/FOXJ1 axis in the MSC-mediated reversal of TEC senescence. The measured values represent the mean ± standard deviation (`X ± s) of three replicate experiments. ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001).

    Article Snippet: Anti-mouse anti-human antibodies against Ki67 and NGF (1R1000 ∼ (th) ServiceBio) were added for staining.

    Techniques: Expressing, Methylation, RNA Sequencing, Immunofluorescence, Marker, Standard Deviation